A update Review
By Walter Sorochan
Posted August 26, 2014 Disclaimer The information provided below is intended for educational purposes only. It is not meant to either directly or indirectly give medical advice or prescribe treatment.
Two Canadian researchers at McGill University in Montreal, Moshe Szyf, a molecular biologist and geneticist and Michael Meaney, a McGill neurobiologist, attended a conference in Spain, in 1992. They met at a bar in Madrid and talked about a new revolutionary idea in genetics: What if diet, chemicals, certain experiences like child neglect, drug abuse or other severe stress could also set off changes to the DNA inside the neurons of a person’s brain, thereby evolving changes in behavior or appearance? That question turned out to be the basis of a new biological science, behavioral epigenetics.
This article explores the new science and the role environment has in activating the DNA to turn good switches on and bad switches off that affect your body and your way of life.
An example of DNA switch:
We have been brainwashed into believing that we inherit most of our good and bad genes [ DNA ] and we are stuck with these the rest of our lives. The traditional belief system or dogma said that if your parents were overweight or obese, had cancer, or diabetes, then you would probably also have these diseases. Buchen: nurturing babies 2010 But this may not true any more!
"You are not controlled by your genetic makeup. Instead, your genetic readout [which genes are turned "on" and which are turned "off"] is primarily determined by your thoughts, attitudes, and perceptions!" Androite: Switching fat off 2013 Gabriel-Method-Revolutionary-DIET Mercola: dogmas & changing DNA 2012 Dashwood: Epigentics: controling DNA 2010 Mithers: weight loss is in head 2007
Epigenetics is the powerful way that food, environment, thoughts and lifestyle impact on our genes and cause the genes to change how they work [ but not change the genes themselves ].
In case you need to refresh the parts of a human cell, here is an imaginary cell and its nucleus, chromatin and DNA:
Behavioral epigenetics is the study of how signals from the environment trigger molecular biological changes that modify what goes on in brain cells. It examines the role of epigenetics in shaping animal (including human) behavior. It seeks to explain how nurture shapes virtually everything that occurs during the life-span [e.g., social-experience, diet and nutrition, and exposure to toxins].
The videos below explain how epigenetics works.
What is epigenetics - Bruce H. Lipton: 1:00 mn.
Video: Dr. Wayne Dyer & Dr. Bruce Lipton - Power of the Mind
7:28 mns long:
Bruce Lipton how science of biology and genetics
works; Length 1:08:52 mns.
So far so good. If you viewed the videos, you should have some understanding of the biochemistry of science behind epigenetics. The illustration below shows that there are two phases to epigenetics. The first phase is the environment that includes many things like food, toxins, socializing, exercise, climate changes, and other activates that stimulate the cell membrane.
The second phase begins with the cell membrane [light blue color] receiving the environmental stimulus, thereafter sending a signal to the nucleus [ purple color ] which stores DNA. The DNA synthesizes special proteins that, in turn, change / adjust protein shape and length. The protein [ made up of amino acids ] is the bridge between genes and traits and is the switch that turns the gene(s) on/off and arouses the mind or belief perception to select a new behavior; the example below of the obese man thinking thin. This 'think thin' perception is a new behavior that rewrites genes into a RNA copy [ but does not change the DNA ], changing the psychic awareness of a fat man being perceived as a new thin man in the mind and cell! The fat cell loses fat. "Mind over matter!"
You may have some confusion about what you viewed because what you were taught is different from the new biology science.
The old beliefs or dogmas about heredity and genetics: The old model has a cell with a nucleus and cytoplasm inside an outer cover or membrane skin. The traditional belief has been that the nucleus is the 'control' center of the cell and perceived as commanding all cell functions. Genes select genes. For over a hundred years we have accepted that the genetic code changes slowly, through the processes of random mutation and natural selection. This is what we learned in our science and medical classes.
Another approach to understanding dogmas and epigenetics by
Bruce Lipton: length 42:41 mns.
In spite of mounting research giving behavioral epigenetics credibility, the new biology is controversial. Buchen: nurturing babies 2010 Mercola: dogmas & changing DNA 2012 "Old dogs do not want to learn new tricks!" The controversy is more about outdated belief than science! Such controversy should not deter us from exploring it and even trying it out.
Educate yourself on how your body works: Story at-a-glance:
Psychology of Change: The other half of epigenetics, the psychology of change, is how you yourself can turn the genes on/off with a new belief system .... using thoughts or perceptions. Numerous psychologists claim to be able to do this with meditation Black: meditation changes DNA 2012 and visualizations, but as yet their explanations and demonstrations lack everyday application and validity. You and others need to be able to activate the belief signal and be able to actually turn selected switches on or off in real time. As independent investigator Sorochan has found out, he understands the science of epigenetics but doesn't know whether he is turning the switches on or off yet. This is the missing link that would make it possible for all of us to use epigenetics in our daily lives!
However, you may have inadvertently switched some/many of your genes on without being aware. For example, your eating "whole plant food complexes," exercising and being in the sun for 20 to 30 minutes [vitamin D] could automatically turn on the good switches. On the other hand you might be turning the bad switches when you are ingesting toxins [ fluoride, chlorine ] in water, smoking cigarettes, eating sugar sweets, or being exposed to toxic heavy metals like mercury or lead, polluted air or contaminated food. These are simple examples of what you may be doing and not be aware of. You are selecting your environment for change. So although the earlier comments that we need more information/research about how to turn the switch for the psychology of change are true, we may actually be doing good and bad environmental changes without being aware that we are.
So why is this new information about epigenetics important for you? Because it has the potential to change how you can successfully lose fat, prevent diseases and disorders and live a longer, happier and healthier life.
The past 100 years were witness to a barrage of highly stressful, life-threatening, anxiety-producing events: wars, large-scale disasters, assassinations, mass murders, and the obliteration of entire cities and the threat of annihilation of millions more people with nuclear weapons. The Overkalix studies in Sweden about poor nutrition affecting the health of future generations Bygren: grandma food affect on grandchildren 2014 and Dutch famine of 1944, known as the Hongerwinter ["Hunger winter"], that took place in the German occupied northern part of the Netherlands Roseboom: Prenatal famine & adult disease 2001, both imply the theory that diseases like cancer and heart disease can originate in the womb.
On the other hand, we have also had many positive life changing happenings like electricity, clean water, women’s right to vote, automobiles, air and space travel, air conditioning, and highway systems, the discoveries of antibiotics, television, the internet and cell phones. Many of these supposed good innovations have had deleterious affects on health of people. Henry A. Nasrallah, MD, asks: "Can there be a transgenerational neurobiological effect on the children and grandchildren of people who have been subjected to life-threatening, traumatic societal events? Could the psychobiology of widespread anxiety and worry (solicitude) be experienced not only by the generation that witnessed and lived through those devastating events, but also by their progeny, who were not yet born during the traumatic events? And could there be epigenetic consequences on a large scale, producing a generation that shares traits induced by the trauma experienced by the previous generation?" Nasrallah global trauma affects generations 2014 Judith Atkinson reviewed research about whole communities being affected by a single experience of trauma by a single member of a community; giving support to Nasrallah's implications! Atkinson: community trauma There is circumstantial research that substantiates the transgrenerational observations of Nasrallah, Atkinson, Bygren, Roseboom and others.
New ongoing findings about "transgenerational effects on animals and humans compel a reevaluation of how scientists perceive environmental health threats. Anway: transgeneration effects fertility 2005 “We have to think more long-term about the effects of chemicals that we’re exposed to every day,” says Lisa Chadwick, a program administrator at the National Institute of Environmental Health Sciences (NIEHS). “This new research suggests they could have consequences not just for our own health and for that of our children, but also for the health of generations to come.” Schmidt: environ effects inheritance 2013
Skinner has shown that insecticides, phthalates, dioxin, and jet fuel, when given to gestating rats during periods of embryonic programming, promote early-onset puberty in female offspring and decreased sperm counts in males, out to the F3 generation. Schmidt: environ effects inheritance 2013
"Chemicals given to pregnant female mice (the F0 generation) interact not only with the fetal offspring (the F1 generation) but also the germ cells developing within those offspring, which mature into the sperm and eggs that give rise to the F2 generation. Thus, the F3 animals are the first generation to be totally unexposed to the original agent. Effects that extend to the F2 generation are known as “multigenerational,” whereas those that extend to the F3 generation are known as “transgenerational.” Transgenerational effects have now been reported for chemicals including permethrin, DEET, bisphenol A, certain phthalates, dioxin, jet fuel mixtures, nicotine, and tributyltin, among others. Most of these findings come from rodent studies. But preliminary evidence that chemical effects can carry over generations in humans is also emerging, although no F3 data have been published yet." Schmidt: environ effects inheritance 2013
The science is good. Most of the epigenetic research began as a hunch in 1992 in a bar in Madrid, Spain. Since then, the support for the hunch has mounted gradually with research picking up steam since 2004. The unique researches may be difficult to understand for persons lacking a biology-genetics background. The research also throws out genetic terms that may be complex. Making matters worse is the inability of many superb researchers to communicate their findings to us. This researcher reviewed many research projects [ see footnotes below ] dealing with epigenetics in an effort to find a researcher who understood the field and who also could communicate the new science in simple terms. Such a researcher is Bruce Lipton.
Lipton explains epigenetics, using animation, in a general way. Lipton's explanation of how the new bio-science of epigenetics works and how it can be used to change people's beliefs and approaches to controlling their body and health is also giving credibility to Gabriel's approach to weight control. Lipton and Gabriel leave a mystery gap in how to implement theory into practice; activating the mind to turn good switches on. The gap is with psychologists theorizing, talking and simulating how to activate the mind for change instead of actually guiding [ giving a confirmation recipe ] people into doing it; that is, actually having people change their belief switch. The proof of this happening is missing! This gap needs more research to put the "proof of the pudding in the eating!" Researchers need to simplify just how "main street people" can implement turning the belief switch epigenetics in their everyday lives. Until this happens, the use of epigenetics in user's hands will remain somewhat of a mystery. These reserved observations should not stop you from trying the new epigenetics out in your personal life. As pointed out earlier, you have been letting your environment dictate your choices and switches by letting others turn on the switches for you [ like mass media advertizing, newspapers and recommendations from others ].
But the science behind turning the belief switches on and off has an excellent graphic communicator in Bruce Lipton.
Although there is much that most persons may not understand about Lipton's epigenetics, and the biological experiments of Cairns, Meaney, Szyf and others, this new science opens the door for a new approach to the practice of medicine, to healing and to better health. New research about what traits new generations may inherit from grandparents, parents and communities should motivate our politicians to review current agricultural and industry practices. Lipton and his college, Rob Williams, point out that changing the belief switch should take 2 to 5 minutes. This contradicts Gabriel's system of weight loss approach requiring length visualizations over months. Obviously, such differences need to be resolved with more good research design.
All this new information should make you aware that you can become an extension of your environment, your thoughts and belief systems, toxic exposures, exposure to sunlight, exercise, and food. The new biology moves you out of victim-blaming others for your problems and toward mastery over your own health. "You Can Take Control of Your Health."
It gives you a recipe for your lifestyle and how to live! It is not just about weight loss and getting rid of excess body fat, but bringing under control many chronic disorders like diabetes, autoimmune disorders and cancer without drugs and expensive therapy.
Your feedback is most appreciated: E-mail to: Author Walter Sorochan
To return to: web-site main page
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"In his new book The Fat Switch, Richard J. Johnson, a professor of medicine and head of the division of Renal Diseases and Hypertension at the University of Colorado-Denver, argues that obesity is a process animals have used to protect themselves during periods of food shortage, and that they have learned to "flip" a switch when they want to gain weight. The switch occurs in the energy factories of the body (mitochondria) and results in the desire to eat more than is needed and to reduce energy output, thus allowing the maximal conversion of food into fat. >Johnson says the real reason people are getting fat is that they have inadvertently activated the "fat switch." In other words, we are eating more not because we are given bigger servings of food, but because we demand bigger servings, and we are exercising less not because we are watching more TV, but we are watching more TV because we have less energy.
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Langer defines mindfulness as the simple act of actively noticing things - with a result of increased health, competence, and happiness; what neuroscience is pointing at now: our experience of everything is formed by the words and ideas we attach to them: e.g. to induce weight loss by substituting the label “exercise” for labor.
Learn genetic traits [ explore activities ] Explore your traits
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Lipton claims that amino acid chains that make up the backbone of proteins receive signals from the quantum field. He goes on to explain that by changing the quantum field we can actually affect how the proteins bind and interrelate to other proteins affecting the systems in the body. The implications of his research has radically change our understanding of life. It shows that genes and DNA do not control our biology; that instead DNA is controlled by signals from outside the cell, including the energetic messages emanating from our positive and negative thoughts. Dr. Liptons's profoundly hopeful synthesis of the latest and best research in cell biology and quantum physics is being hailed as a major breakthough, showing that our bodies can be changed as we retrain our thinking.
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An example:"These findings suggest that diet can cause changes to genes that are passed down though generations by the males in a family, and that these alterations can affect susceptibility to certain diseases. --- Epigenetics involves genetic control by factors other than an individual's DNA sequence. Epigenetic changes can switch genes on or off and determine which proteins are transcribed. --- Within cells, there are three systems that can interact with each other to silence genes: DNA methylation, histone modifications, and RNA-associated silencing. --- Because so many diseases, such as cancer, involve epigenetic changes, it seems reasonable to try to counteract these modifications with epigenetic treatments. These changes seem an ideal target because they are by nature reversible, unlike DNA sequence mutations. The most popular of these treatments aim to alter either DNA methylation or histone acetylation."
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"... discovered that the type and amount of nurturing a mother rat provides in the early weeks of the rat's infancy determines how that rat responds to stress later in life. Immediately after birth, they found that methyl groups repress the glucocorticoid receptor gene in all rat pups, making the gene unable to unwind from the histone in order to be transcribed, causing a decreased stress response. Nurturing behaviors from the mother rat were found to stimulate activation of stress signaling pathways that remove methyl groups from DNA."
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